Novo Nordisk is handing over $1.1 billion in cash to buy Forma Therapeutics in hopes that the clinical-stage biotech’s assets will help build a leading portfolio in sickle cell disease (SCD).
The Denmark pharma giant will acquire all outstanding shares of the Massachusetts biotech’s stock for $20 apiece—a total equity value of $1.1 billion, according to a Sept. 1 release.
Forma—a 2011 Fierce 15 winner—and debuted on the market in 2020 with an upsized $278 million IPO, the fifth largest biotech IPO of the year. Genentech veteran Frank Lee helps the company. The biotech is centered around etavopivat, a once-daily, selective pyruvate kinase-R activator that is being developed to treat rare genetic blood disorders such as SCD.
Etavopivat is an oral med that has snagged FDA fast track, rare pediatric disease and orphan drug tags.
“We have an ambition to build a leading portfolio with standalone and combination treatments to tackle the complications and underlying causes of sickle cell disease,” said Ludovic Helfgott, executive vice president and head of rare disease at Novo Nordisk. The debilitating, life-threatening disease affects around 17 million people worldwide.
Etavopivat is being evaluated in a global phase 2/3 SCD trial, as well as in a phase 2 trial in patients with transfusion-dependent SCD and a genetic blood disorder known as thalassemia. Earlier phase 1 data showed etavopivat improved anemia and red blood cell health and appeared to be safe and well-tolerated among patients with SCD.
After Novo Nordisk’s tender offer is completed, the company’s acquisition subsidiary will merge into Forma Therapeutics. Novo is dipping into its financial reserves to pay for the acquisition, so the transaction isn’t expected to impact its previously shared operating profit outlook for 2022.
The transaction is set to close during the fourth quarter of this year.
By Gabrielle Masson
Source: fiercebiotech.com
The United Arab Emirates (UAE) Ministry of Health and Prevention (MoHAP) has established a partnership with Novo Nordisk Pharma Gulf focusing on the creation of a national scientific guide for obesity management and weight control. The collaboration also aims to enhance public awareness of cardiovascular diseases and their complications.
Pharma giant Eli Lilly is teaming up with Haya Therapeutics in a $1bn deal to find multiple regulatory-genome-derived RNA-based drug targets, as it eyes up new targets in obesity. Under the deal, the companies will use Haya’s proprietary regulatory genome discovery platform to identify and validate long non-coding RNA (lncRNA) targets for developing potential treatments for obesity and related metabolic disorders.
The sale includes custom formulation and contract manufacturing capabilities for the nutrition market from the production facilities in New Jersey and Utah in the United States, and Tamaulipas, Mexico. Financial terms of the transaction were not disclosed.
